Tissue Biomechanics and Mechanobiology

The aim here is to study the basic mechanisms of bone and cartilage homeostasis and remodelling as well as the pathomechanisms of degeneration influenced by mechanical loading and unloading. We investigate the modelling and remodelling of both bone and cartilage from the cell to the whole-body level with a focus on:

• Interaction between cells and the extracellular matrix (ECM)
• Transduction pathways involved in mechanical signalling
• Osteoarthritis and osteoporosis